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Additionally, the concentration of AOD9604 in the synovial fluid after injection was estimated to be about 0.19 mg/mL, similar to concentrations used in previous GH injection studies in animal models

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A double-blind, placebo-controlled trial in 95 patients with irritable bowel syndrome or inflammatory bowel disease and normal B12 levels found no significant improvements in fatigue, although B12 levels increased in the B12 group who received 1000 µg per day per os (p.o.) for 8 weeks (form not reported)